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Důvěra Masakr Následuj nás asics are trimeric proton gated Vyřazeno Nedávno pilulka

Gating choreography and mechanism of the human proton-activated chloride  channel ASOR
Gating choreography and mechanism of the human proton-activated chloride channel ASOR

ASIC and ENaC type sodium channels: conformational states and the  structures of the ion selectivity filters - Hanukoglu - 2017 - The FEBS  Journal - Wiley Online Library
ASIC and ENaC type sodium channels: conformational states and the structures of the ion selectivity filters - Hanukoglu - 2017 - The FEBS Journal - Wiley Online Library

The function and regulation of acid‐sensing ion channels (ASICs) and the  epithelial Na+ channel (ENaC): IUPHAR Review 19 - Boscardin - 2016 -  British Journal of Pharmacology - Wiley Online Library
The function and regulation of acid‐sensing ion channels (ASICs) and the epithelial Na+ channel (ENaC): IUPHAR Review 19 - Boscardin - 2016 - British Journal of Pharmacology - Wiley Online Library

Acid-sensing ion channels emerged over 600 Mya and are conserved throughout  the deuterostomes | PNAS
Acid-sensing ion channels emerged over 600 Mya and are conserved throughout the deuterostomes | PNAS

Coupling structure with function in acid‐sensing ion channels: challenges  in pursuit of proton sensors - Rook - 2021 - The Journal of Physiology -  Wiley Online Library
Coupling structure with function in acid‐sensing ion channels: challenges in pursuit of proton sensors - Rook - 2021 - The Journal of Physiology - Wiley Online Library

Identification of a unique Ca2+-binding site in rat acid-sensing ion  channel 3 | Nature Communications
Identification of a unique Ca2+-binding site in rat acid-sensing ion channel 3 | Nature Communications

Conformational dynamics and role of the acidic pocket in ASIC pH-dependent  gating | PNAS
Conformational dynamics and role of the acidic pocket in ASIC pH-dependent gating | PNAS

Acid-sensing ion channels: dual function proteins for chemo-sensing and  mechano-sensing | Journal of Biomedical Science | Full Text
Acid-sensing ion channels: dual function proteins for chemo-sensing and mechano-sensing | Journal of Biomedical Science | Full Text

RCSB PDB - 5WKU: Structure of an acid sensing ion channel in a resting  state with barium
RCSB PDB - 5WKU: Structure of an acid sensing ion channel in a resting state with barium

Architectural and Functional Similarities between Trimeric ATP-Gated P2X  Receptors and Acid-Sensing Ion Channels - ScienceDirect
Architectural and Functional Similarities between Trimeric ATP-Gated P2X Receptors and Acid-Sensing Ion Channels - ScienceDirect

Acid-Sensing Ion Channels as Potential Therapeutic Targets in  Neurodegeneration and Neuroinflammation
Acid-Sensing Ion Channels as Potential Therapeutic Targets in Neurodegeneration and Neuroinflammation

RCSB PDB - 6AVE: Structure of an acid sensing ion channel in a resting  state at high pH
RCSB PDB - 6AVE: Structure of an acid sensing ion channel in a resting state at high pH

Gating scheme Cartoon representation of the proton-dependent gating... |  Download Scientific Diagram
Gating scheme Cartoon representation of the proton-dependent gating... | Download Scientific Diagram

Proton-gated currents in SGNs. (A) Current–pH curves. ASIC activation... |  Download Scientific Diagram
Proton-gated currents in SGNs. (A) Current–pH curves. ASIC activation... | Download Scientific Diagram

Novel Insights into Acid-Sensing Ion Channels: Implications for  Degenerative Diseases
Novel Insights into Acid-Sensing Ion Channels: Implications for Degenerative Diseases

Solved Acid-sensitive ion channels (ASICs) are a family of | Chegg.com
Solved Acid-sensitive ion channels (ASICs) are a family of | Chegg.com

Pore architecture and ion sites in acid-sensing ion channels and P2X  receptors. - Abstract - Europe PMC
Pore architecture and ion sites in acid-sensing ion channels and P2X receptors. - Abstract - Europe PMC

Structure of the Acid-sensing ion channel 1 in complex with the gating  modifier Psalmotoxin 1 | Nature Communications
Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1 | Nature Communications

Kinetic analysis of ASIC1a delineates conformational signaling from proton-sensing  domains to the channel gate | eLife
Kinetic analysis of ASIC1a delineates conformational signaling from proton-sensing domains to the channel gate | eLife

Proton-gated currents in SGNs. (A) Current–pH curves. ASIC activation... |  Download Scientific Diagram
Proton-gated currents in SGNs. (A) Current–pH curves. ASIC activation... | Download Scientific Diagram

ENAC, Degenerins, ASICs, and Related Channels | SpringerLink
ENAC, Degenerins, ASICs, and Related Channels | SpringerLink

Acid-sensing ion channels emerged over 600 Mya and are conserved throughout  the deuterostomes | PNAS
Acid-sensing ion channels emerged over 600 Mya and are conserved throughout the deuterostomes | PNAS

Proton-mediated Conformational Changes in an Acid-sensing Ion Channel* -  Journal of Biological Chemistry
Proton-mediated Conformational Changes in an Acid-sensing Ion Channel* - Journal of Biological Chemistry

International Union of Basic and Clinical Pharmacology. XCI. Structure,  Function, and Pharmacology of Acid-Sensing Ion Channels and the Epithelial  Na+ Channel | Pharmacological Reviews
International Union of Basic and Clinical Pharmacology. XCI. Structure, Function, and Pharmacology of Acid-Sensing Ion Channels and the Epithelial Na+ Channel | Pharmacological Reviews

Overview of the acid-sensing ion channel 1 (ASIC1) crystal structure.... |  Download Scientific Diagram
Overview of the acid-sensing ion channel 1 (ASIC1) crystal structure.... | Download Scientific Diagram

Potentiation of proton-gated current in CHO cells expressing ASICs.... |  Download Scientific Diagram
Potentiation of proton-gated current in CHO cells expressing ASICs.... | Download Scientific Diagram

Determinants of proton sensitivity in broadly related ASICs. (A)... |  Download Scientific Diagram
Determinants of proton sensitivity in broadly related ASICs. (A)... | Download Scientific Diagram